A polymorphism of the CYP17 gene related to sex steroid metabolism is associated with female-to-male but not male-to-female transsexualism. Note: Content may be edited for style and length. Although the etiology of gender dysphoria or transsexualism is still unknown, different neuroimaging studies show that structural and functional changes of the brain result from this sexual incongruence.
Corresponding author. Gender identity disorder in twins: a review of the case report literature.
J Neurosci. Moreover, this research group reported significant differences between MtF transgenders and both male and female controls in the superior longitudinal fasciculus, corticospinal tract, forceps minor and anterior cingulum. Events Society going viral!
Emory et al. An evolutionary view of 'gay genes'. They reported higher degree centrality in the primary somatosensory cortex and the bilateral superior parietal lobule for transgender subjects. Read more: Born this way? Structural connectivity networks of transgender people.
The authors found extensive significant differences in mean diffusivity between transgenders and male and female controls in most white matter tracts.