Menu Abstract. As previously reported by us and others 64 - 66intrastriatal injection of AMPA induces robust neuronal death within 24h followed by a neuroinflammatiory response. Figure 6. Adv Exp Med Biol. Twenty-four hours later, the rats were anesthetized again as described above and scanned with a 3T cryogen-free MRS scanner with a quadrature, rat head coil MR Solutions, Guildford, UK 3435 to assess oedema i.
Banister SD, Kassiou M. Find articles by Marie-Claude Asselin.
Subject Index. Hippocampus and fornix. Studies have found that oxytocin improves spatial memory. This story is a common refrain I hear when discussing my research on sex differences in the brain. These conditions provide the opportunity to ask whether brain sex matches gonadal sex.
CAH girls are born with masculinized genitalia, for example, due to their in utero androgen exposure, while CAIS boys appear as normal girls when born due to the lack of differentiation of the external male sex organs. For these reasons, researchers assiduously avoid experimenting with female animals.
This is not to say that everything is different. This highlights how much we have to learn about the nature of sex differences in neuropsychiatric disorders and the multiple ways in which some differences can manifest. Additionally, there are differences in memory skills between males and females which may suggest a difference in the hippocampal volume HCV.
A counter-theory is that girls are underdiagnosed for ASD due to physician bias and a different presentation, with fewer social and cognitive defects.
Immunocytochemical localization of the sigma 1 receptor in the adult rat central nervous system. Curr Alzheimer Res. Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Overall, the results of the pre-saturation studies and the presence of specific binding throughout the brain are in agreement with the previous reports 10 , Epidemiology and risk factors of dementia.
S1R expression has therefore been envisaged as a potential biomarker for neuronal function in health and diseases.