However, the contribution of oral-genital contact via cunnilingus and oral-anal contact is still unknown. N Engl J Med. The absence of HIV transmission via saliva is attributed to two factors: saliva contains a very small amount of HIVand several inhibitory components in oral secretions mean saliva acts to protect susceptible cells from HIV infection, Else, personal communication.
Ballweber L, et al. Mucosal inflammation gingivitis does not increase oral SIV transmission, but does impact immune activation following SIV infection. Human submandibular saliva aggregates HIV. Infect Control Hosp Epidemiols.
Therefore, it is critical that we thoroughly understand the multiple routes of virus exposure that can lead to HIV infection, including rectal, vaginal, penile, and oral HIV exposure. Determination of salivary levels of mucin and amylase in chronic periodontitis patients.
Cited by: 71 articles Oral sex and hiv aids in Henderson Journal of Research on Adolescence. Free full text. In fact, there has not been a reported case of transmission from a person with an undetectable viral load in any clinical trial.
Jochimsen EM. Nova Science Publishers; Varela M, et al. Marthas ML, et al. Introduction The global spread of human immunodeficiency virus HIV is dependent on the ability of the virus to efficiently cross from one host to the next by traversing mucosal membranes.